CEFTIZOXIME 1g, 500mg

Vial Ceftizoxime 1g, 500mg ( contains strile powder for injection)

Generic Name of ProductBrand NameDosage Form StrengthPharmacologic GroupTherapeutic GroupUnit Per Pack
Ceftizoxime-Vial500/1000CephalosporinAntibacterial12

Indications And Usage
Lower Respiratory Tract Infections caused by Klebsiella spp.; Proteus mirabilis; Escherichia coli; Haemophilus influenzae including ampicillin­resistant strains; Staphylococcus aureus (penicillinase­ and nonpenicillinase­producing); Serratia spp.; Enterobacter spp.; Bacteroides spp.; and Streptococcus spp. including S. pneumoniae, but excluding enterococci.
Administration
The usual adult dosage is 1 or 2 grams of ceftizoxime for injection, USP) every 8 to 12 hours. Proper dosage and route of administration should be determined by the condition of the patient, severity of the infection, and susceptibility of the causative organisms.
Contraindications
ceftizoxime for injection, USP) is contraindicated in patients who have known allergy to the drug.
Precautions
As with all broad­spectrum antibiotics, ceftizoxime for injection, USP) should be prescribed with caution in individuals with a history of gastrointestinal disease, particularly colitis.
Adverse Reactions
Stevens­Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, serum­ sickness like reaction, toxic nephropathy, aplastic anemia, hemorrhage, prolonged prothrombin time, elevated LDH, pancytopenia, and agranulocytosis.
Pregnancy and lactation
Category B
Renal and liver Impairment
In patients undergoing hemodialysis, no additional supplemental dosing is required following hemodialysis; however, dosing should be timed so that the patient receives the dose at the end of the dialysis.
Laboratory Tests
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