Indications And Usage

Triamcinolone belongs to a class of drugs called corticosteroids. It prevents the release of substances in the body that cause inflammation.

Triamcinolone oral (taken by mouth) is used to treat many different conditions such as allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, or breathing disorders

Allergic states, Dermatologic diseases, Endocrine disorders, Gastrointestinal diseases, Hematologic disorders, Miscellaneous, Neoplastic diseases, Nervous system, Ophthalmic diseases, Renal diseases, Respiratory diseases, Rheumatic disorders

Administration

The initial dose of Triamcinolone-40 Injection and Triamcinolone-80 Injection may vary from 2.5 mg to 100 mg per day depending on the specific disease entity being treated .However, in certain overwhelming, acute, life-threatening situations, administration in dosages exceeding the usual dosages may be justified and may be in multiples of the oral dosages.

Contraindications

Triamcinolone-40 Injection and Triamcinolone-80 Injection are contraindicated in patients who are hypersensitive to any components of this product

Precautions

This product, like many other steroid formulations, is sensitive to heat. Therefore, it should not be autoclaved when it is desirable to sterilize the exterior of the vial.The lowest possible dose of corticosteroid should be used to control the condition under treatment. When reduction in dosage is possible, the reduction should be gradual. Since complications of treatment with glucocorticoids are dependent on the size of the dose and the duration of treatment, a risk/benefit decision must be made in each individual case as to dose and duration of treatment and as to whether daily or intermittent therapy should be used. Kaposi’s sarcoma has been reported to occur in patients receiving corticosteroid therapy, most often for chronic conditions. Discontinuation of corticosteroids may result in clinical improvement.

Adverse Reactions

Aggression, agitation, anxiety, blurred vision, decrease in the amount of urine, dizziness, fast, slow, pounding, or irregular heartbeat or pulse, headache, irritability, mental depression, mood changes, nervousness, noisy, rattling breathing, numbness or tingling in the arms or legs, pounding in the ears, shortness of breath, swelling of the fingers, hands, feet, or lower legs, trouble thinking speaking or walking

troubled breathing at rest, weight gain

Pregnancy and lactation

Pregnancy: Corticosteroids have been shown to be teratogenic in many species when given in doses equivalent to the human dose. Animal studies in which corticosteroids have been given to pregnant mice, rats, and rabbits have yielded an increased incidence of cleft palate in the off-spring. There are no adequate and well-controlled studies in pregnant women. Corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Infants born to mothers who have received corticosteroids during pregnancy should be carefully observed for signs of hypoadrenalism.

Breastfeeding: Systemically administered corticosteroids appear in human milk and could suppress growth, interfere with endogenous corticosteroid production, or cause other untoward effects. Caution should be exercised when corticosteroids are administered to a nursing woman.

Renal and liver Impairment

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Laboratory Tests